Prozac is a prescription medicine that works for depression, major depressive disorder, obsessive-compulsive disorder, and panic attacks. The generic name for it is fluoxetine. It is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). It affects the levels of neurotransmitters in the brain, which include serotonin. Serotonin affects moods and emotions. Prozac helps in keeping these levels balanced.

Prozac and Its Side Effects

Generally, Prozac is a commonly prescribed, safe drug for depression. People diagnosed with any of the above disorders will experience some relief from their symptoms when taking Prozac. Like any medication, possible side effects might be felt. These include:

Most Common:

  • Hives, itching, skin rash
  • Unable to sit still
  • Restlessness


  • Fever
  • Chills
  • Joint pain
  • Muscle Pain

Mostly Rare:

  • Anxiety
  • Cold Sweats
  • Confusion
  • Convulsions
  • Pale, cool skin
  • Diarrhea
  • Trouble concentrating
  • Drowsiness
  • and more

Possible Interaction Effects From Prozac
with Other Substances

It is possible to have an adverse reaction when taking Prozac with other substances. Street drugs such as MDMA/”ecstasy,” natural supplements like St. John’s wort, migraine medicines, sleep medication, and other antidepressants can cause Serotonin Syndrome (SS). Illegal drugs like LSD (lysergic acid diethylamide), cocaine, and amphetamines can also contribute to SS.

This syndrome occurs when there is a buildup of serotonin in the brain. It can be fatal. 

Symptoms from SS can begin from minutes to hours, as noted by

  • Diarrhea
  • Rapid eye movement
  • Agitation
  • Restlessness
  • Fast heartbeat and high blood pressure
  • Hallucinations
  • Increased body temperature
  • Loss of coordination
  • Nausea and vomiting
  • Overactive reflexes
  • Rapid changes in blood pressure
  • It is best to be treated in the hospital for SS because medical personnel can continuously monitor the person’s health condition to prevent death.

Potential Overdose from Prozac


There is a potential probability of overdosing on Prozac, as noted by Healthline.  It is smart to know what to look for if someone seems like they are having overdose symptoms.  These effects start off mild and worsen over time.

Signs of overdose: (not in any order of occurrence)

  • Nausea
  • Vomiting
  • Headache
  • Drowsiness
  • Blurred vision
  • Tremors
  • High fever

Serious overdose signs/symptoms:

  • Uncontrollable muscle spasms
  • Fast heart rate
  • Dilated pupils
  • Difficulty breathing
  • Stiff muscles
  • Seizures
  • Mania
  • Coma

Help for Someone Who’s Overdosed

The most imperative thing to do when someone is overdosing is to call 911.  Try to remain calm when on the phone. Also, try to keep the person awake until first responders arrive.

Relay this information to the person on the phone:

  • The person’s name, age, height, weight, and gender
  • Amount of Prozac taken
  • If they have taken any other drugs, herbs, supplements, or drank alcohol
  • If the person has any other medical conditions or mental health conditions

Addiction Treatment for Prozac

Prozac is a familiar drug that many people take to alleviate several mental health disorders. While you may feel OK when taking it, it is best not to quit taking it abruptly. Quitting Prozac suddenly can cause severe depressive thoughts and suicide ideation, along with other serious mental and physical symptoms.

If you want to stop taking Prozac, contact your doctor. He or she will taper the dosage so you can safely exit Prozac use. If you feel you may be addicted to Prozac, you can call the experienced, licensed staff at Family Recovery Specialists. They are available 24 hours a day, seven days a week. 

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